The pills you pop may make you feel better, but they could be fatal to your pet. Just last year, the ASPCA Animal Poison Control Center (APCC) handled 89,000 cases of pets exposed to human medications.

Here’s what to watch out for:

NSAIDs
According to the APCC, NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen or naproxen are the most common cause of pet poisoning in small animals, and can cause serious problems even in minimal doses. Pets may experience stomach and intestinal ulcers and—in the case of cats—kidney damage.

Antidepressants
Antidepressants can cause vomiting and lethargy and certain types can lead to serotonin syndrome—a condition marked by agitation, elevated body temperature, heart rate and blood pressure, disorientation, vocalization, tremors and seizures.

Acetaminophen
Cats are especially sensitive to acetaminophen, which can damage red blood cells and interfere with their ability to transport oxygen. In dogs, it can cause liver damage and, at higher doses, red blood cell damage.

Methylphenidate (for ADHD)
Medications used to treat ADHD (Attention Deficit Hyperactivity Disorder) in people act as stimulants in pets and can dangerously elevate heart rates, blood pressure and body temperature, as well as cause seizures.

Fluorouracil
Fluorouracil—an anti-cancer drug—is used topically to treat minor skin cancers and solar keratitis in humans. It has proven to be rapidly fatal to dogs, causing severe vomiting, seizures and cardiac arrest even in those who’ve chewed on discarded cotton swabs used to apply the medication.

Isoniazid
Isoniazid is particularly toxic for dogs because they don’t metabolize it as well as other species. It can cause a rapid onset of severe seizures that may ultimately result in death.

Pseudoephedrine
Pseudoephedrine is a popular decongestant in many cold and sinus products, and acts like a stimulant if accidentally ingested by pets. In cats and dogs, it causes elevated heart rates, blood pressure and body temperature as well as seizures.

Anti-diabetics
Many oral diabetes treatments—including glipizide and glyburide—can cause a major drop in blood sugar levels of affected pets. Clinical signs of ingestion include disorientation, lack of coordination and seizures.

Vitamin D derivatives
Even small exposures to Vitamin D analogues like calcipotriene and calcitriol can cause life-threatening spikes in blood calcium levels in pets. Clinical signs of exposure—including vomiting, loss of appetite, increased urination and thirst due to kidney failure—often don’t occur for more than 24 hours after ingestion.

Baclofen
Baclofen is a muscle relaxant that can impair the central nervous systems of cats and dogs. Some symptoms of ingestion include significant depression, disorientation, vocalization, seizures and coma, which can lead to death.

To help avoid accidental exposure, the ASPCA recommends keeping all medications out of reach of animals. If your pet does swallow any meds, stay calm and try to assess how many are left in the bottle versus how many might have been consumed. This dosage information is crucial for veterinarians when assigning your pet’s risk level and determining a proper course of treatment.

If you suspect your pet has ingested any human medications—or other toxic substances—immediately call your vet or the ASPCA Animal Poison Control Center’s 24-hour hotline at (888) 426-4435. Time is of the essence and could mean the difference between life and death for your dog.

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